ISSN 1662-4009 (online)

ey0015.1-1 | New mechanisms | ESPEYB15

1.1 Female sexual behavior in mice is controlled by kisspeptin neurons

V Hellier , O Brock , M Candlish , E Desroziers , M Aoki , C Mayer , R Piet , A Herbison , WH Colledge , V Prevot , U Boehm , J Bakker

To read the full abstract: Nat Commun 2018;9.400Pheromones play a crucial role to identify potential mates and sexual motivation in mice. These molecules are detected by a specialized circuit which initiates in the nasal septum and then relies on GnRH neurons in the hypothalamus in a sex-dependent manner. Female pheromones induce LH/testosterone release in male mice whereas male pheromones i...